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    Non-commercial:¥1500(Polyclonal antibodies)/Unit  
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CZRZ Catalog ID: PA2
Product: 14-3-3 b/a
Abbreviation: KCIP-1
Isotype: IgG2a
Cellular Localization: Cytoplasm
Antibody type: Mouse Monoclonal Antibody
Genecard: The 14-3-3 proteins are a family of proteins involved in the regulation of apoptosis, mitogenic signaling and cell-cycle checkpoints. The 14-3-3 proteins are thought to be key regulators of signal transduction events mediated through their binding to serine-phosphorylated proteins. Through binding Bad, 14-3-3 prevents apoptosis by sequestering Bad to the cytosol. The 14-3-3 proteins are also Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. They bind to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
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Species Reactivity: Human, mouse, rat, Zebrafish
Antibody Description: pdf
Recommended Dilutions:: WB: 1:1,000-1:2,000 ICC: 1:100 IHC: 1:200
Size: 100ul liquid
Phenotype:
Note:
14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1