CZRZ Catalog ID:	MA70
Product:	p53
Abbreviation:	TP53
Isotype:	IgG
Cellular Localization:	Cytoplasm, Nucleus, Endoplasmic reticulum, Mitochondrion matrix
Antibody type:	Recombinant Rabbit Monoclonal Antibody
Genecard:	The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair or apoptosis. It is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. P53 is found in increased amounts in a wide variety of transformed cells. P53 is frequently mutated or inactivated in about 60% of cancers.
NoteInfo:	该抗体为CZRC与杭州华安生物技术有限公司（华安公司）合作开发，在CZRC下单订购即可享有团购价格（在线订购时请在上传汇款凭证时上传此文件）。CZRC会将有关订单转给华安公司，该抗体订单的付款、发货、售后及服务均由华安公司负责。 * 特别提醒：当您订购抗体时，勿需向CZRC进行支付；因CZRC网站有统一的订购流程，请您在“汇款凭证处”按要求上传此文件即可。
Species Reactivity:	Human, Zebrafish
Antibody Description:	pdf
Recommended Dilutions::	WB: 1:1,000-1:5,000 ICC: 1:50-1:200
Size:	100ul liquid