Search CZRC
Search CZRC for
Fish Lines
ESTs/cDNAs
Antibodies
Others
Anything
Construct
Genotype
Allele
Affected Gene
Line Type
Phenotype
CZRC Catalog ID
Anything
Gene Symbol (Abbreviation)
Gene Name
EST/cDNA Name
Anatomy Structure
Anything
Structure Labeled
Antibody Name
Anything
Product Name
Note
Login
|
Register
Chinese
|
English
Home
About CZRC
Brief Introduction
CZRC Council
Staff Members
Resources
Wild-Type Line
Mutant Line
Transgenic Line
Antibody-list
Antibodies-list1
Antibodies-list2
ESTs/cDNAs
Plasmids
Cell Lines
For Toxicology (毒理学)
Paramecia (草履虫)
Price Units (补差价)
ZKO Project
Technical Service
Transgenic Service
Knock out Service
Zebrafish Care & Health
Training Courses
Make Submissions
Guidelines for Submitting Fish
Submit a Fish Line
CZRC License Agreement
View Information
Prices
Payment Information
Guidelines for Ordering
Material Transfer Agreement (MTA)
Protocols
Health Report
Contact Us
Resource & Service
Wild-type Lines
Mutant Lines
Transgenic Lines
Transgenic Service
Knockout Service
Paramecia
Make Submissions
Guidelines for Submitting Fish
Submit a Fish Line
CZRC License Agreement
View Information
Prices
Payment Information
Guidelines for Ordering
Material Transfer Agreement (MTA)
Protocols
Health Report
Home:
Resources
>
Antibodies-list1
基准单价:
Commercial:¥3500(monclonal antibodies)/
Unit
Non-commercial:¥1750(monclonal antibodies)/
Unit
Price Detail
The CZRC is a non-profit organization. The prices we charge for products and services are to offset some of the actual costs we incur.
Please acknowledge the CZRC in all publications resulting from the materials and/or services we are providing to you. Thank you!
Number:
CZRZ Catalog ID:
MA7
Product:
FOXO1A
Abbreviation:
FOXO1
Isotype:
IgG
Cellular Localization:
Cytoplasm, Nucleus
Antibody type:
Recombinant Rabbit Monoclonal Antibody
Genecard:
FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. These translocations result in the fusion of the amino terminus of Pax-3 or Pax-7, including the paired box and homeodomain DNA-binding domains, with the carboxy-terminus of FKHR, which contains a transcriptional activation domain. The Pax-3/FKHR fusion protein appears to function as an oncogenic transcription factor that enhances the activation of normal Pax-3 target genes.
NoteInfo:
该抗体为CZRC与杭州华安生物技术有限公司(华安公司)合作开发,在CZRC下单订购即可享有团购价格
(
在线订购时请在上传汇款凭证时上传
此文件
)
。CZRC会将有关订单转给华安公司,该抗体订单的付款、发货、售后及服务均由华安公司负责。
* 特别提醒:当您订购抗体时,勿需向CZRC进行支付;因CZRC网站有统一的订购流程,请您在“
汇款凭证处
”按要求上传
此文件
即可
。
Species Reactivity:
Human, Mouse, Rat, Zebrafish
Antibody Description:
pdf
Recommended Dilutions::
WB: 1:1,000-1:2,000 ICC: 1:50-1:200 IHC: 1:50-1:200
Size:
100ul liquid
Phenotype:
Note:
Forkhead box protein O1, Forkhead box protein O1A, Forkhead in rhabdomyosarcoma
Links:
国家水生生物资源库
EENDB
ZAP
ZHA, US
AZPF
TZCF
ZOMB
NBRP-Zebr
EZRC
ZIRC
ZFIN
More
© China Zebrafish Resource Center. All rights reserved.
CZRC Home
|
Guidelines for Ordering
|
Technical Service
|
FAQ
|
Contact Us
Web Support:
Taizhou Xing-Ao Network Technology Co., Ltd.