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    Non-commercial:¥1500(Polyclonal antibodies)/Unit  
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CZRZ Catalog ID: PA5
Product: AKR7A2
Abbreviation: AFB1-AR 1,SSA reductase
Isotype: IgG1
Cellular Localization: Cytoplasm, Golgi apparatus
Antibody type: Mouse Monoclonal Antibody
Genecard: Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene. It catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate and may have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). AKR7A2 has broad substrate specificity and NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). AKR7A2 can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro) and reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
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Species Reactivity: Human, Zebrafish
Antibody Description: pdf
Recommended Dilutions:: WB: 1:1,000-1:2,000 ICC: 1:200
Size: 100ul liquid
Phenotype:
Note:
Aflatoxin B1 aldehyde reductase member 2, AFB1 aldehyde reductase 1, Aldoketoreductase 7 ,Succinic semialdehyde reductase