• 基准单价:
    Commercial:¥3000(Polyclonal antibodies)/Unit  
    Non-commercial:¥1500(Polyclonal antibodies)/Unit  
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CZRZ Catalog ID: PA19
Product: SMAD3
Abbreviation: MAD homolog 3, Mad3,Mothers against DPP homolog 3, hMAD-3, SMAD 3, Smad3, hSMAD3
Isotype: IgG
Cellular Localization: Cytoplasm, Nucleus
Antibody type: Rabbit Polyclonal Antibody
Genecard: Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation. Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.
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Species Reactivity: Human, mouse, rat, Zebrafish
Antibody Description: pdf
Recommended Dilutions:: ICC: 1:50-1:200 IHC: 1:50-1:200 FC: 1:50-1:100 WB: 1:500-1:1,000
Size: 100ul liquid
Phenotype:
Note:
Mothers against decapentaplegic homolog 3, JV15-2, SMAD family member 3