CZRZ Catalog ID:	MA69
Product:	GPX4
Abbreviation:	PHGPx, GPx-4, GSHPx-4
Isotype:	IgG
Cellular Localization:	Mitochondrion.
Antibody type:	Recombinant Rabbit Monoclonal Antibody
Genecard:	Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.
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Species Reactivity:	Human, Mouse, Rat, Zebrafish
Antibody Description:	pdf
Recommended Dilutions::	WB: 1:500-1:2,000 IHC: 1:50-1:200
Size:	100ul liquid