CZRZ Catalog ID:	MA52
Product:	TDP43
Abbreviation:	RNA polymerase II subunit B1, POLR2A
Isotype:	IgG
Cellular Localization:	Nucleus
Antibody type:	Recombinant Rabbit Monoclonal Antibody
Genecard:	DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division. Can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat. Stabilizes the low molecular weight neurofilament (NFL) mRNA through a direct interaction with the 3' UTR
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Species Reactivity:	Human, Mouse, Rat, Zebrafish
Antibody Description:	pdf
Recommended Dilutions::	WB: 1:1,000-1:5,000 ICC: 1:100-1:500 IHC: 1:50-1:200 FC: 1:50-1:100 IP: 1:10-1:50
Size:	100ul liquid