CZRZ Catalog ID:	MA42
Product:	Glucocorticoid Receptor
Abbreviation:	GR, NR3C1
Isotype:	IgG
Cellular Localization:	Cytoplasm, Nucleus, Mitochondrion
Antibody type:	Recombinant Rabbit Monoclonal Antibody
Genecard:	The glucocorticoid receptor (GR) is a ubiquitously expressed transcription factor that mediates the effects of glucocorticoids. The most abundant isoform is GR α. GR induces or represses the expression of genes in response to glucocorticoids, mediating such processes as apoptosis, cell growth and differentiation. A significant class of genes suppressed by GR is controlled by the transcription factor AP-1. GR has also been shown to be the limiting factor in the induction of gene expression by glucocorticoids. It has been revealed that GR forms a complex with HSP 90, rendering the non-ligand bound receptor transcriptionally inactive. More importantly, mutant GRs lacking the signaling domain remain constitutively active.
NoteInfo:	该抗体为CZRC与杭州华安生物技术有限公司（华安公司）合作开发，在CZRC下单订购即可享有团购价格（在线订购时请在上传汇款凭证时上传此文件）。CZRC会将有关订单转给华安公司，该抗体订单的付款、发货、售后及服务均由华安公司负责。 * 特别提醒：当您订购抗体时，勿需向CZRC进行支付；因CZRC网站有统一的订购流程，请您在“汇款凭证处”按要求上传此文件即可。
Species Reactivity:	Human, Mouse, Rat, Zebrafish
Antibody Description:	pdf
Recommended Dilutions::	WB: 1:1,000-1:5,000 FC: 1:50-1:100
Size:	100ul liquid