CZRZ Catalog ID:	MA18
Product:	VCAM1
Abbreviation:	V-CAM 1, VCAM-1
Isotype:	IgG
Cellular Localization:	Membrane
Antibody type:	Recombinant Rabbit Monoclonal Antibody
Genecard:	Cell adhesion molecules are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thought to play an important role in embryogenesis and development. Neuronal cell adhesion molecule (NCAM) expression is observed in a variety of human tumors including neuroblastomas, rhabdomyosarcomas, Wilms' tumors, Ewing's sarcomas and some primitive myeloid malignancies. The intracellular adhesion molecule-1 (ICAM-1), also referred to as CD54, is an integral membrane protein of the immunoglobulin superfamily and recognizes the B2а1 and B2аM integrins. PECAM-1 (platelet/endothelial cell adhesion molecule-1), also referred to as CD31, is a glycoprotein expressed on the cell surfaces of monocytes, neutrophils, platelets and a subpopulation of T cells. VCAM-1 (vascular cell adhesion molecule-1) was first identified as an adhesion molecule induced on human endothelial cells by inflammatory cytokines such as IL-1, tumor necrosis factor (TNF) and lipopolysaccharide (LPS). The KALIG gene encodes a nerve cell adhesion molecule (NCAM) -like protein and is deleted in 66% of patients with Kallmann's syndrome, anosmia with secondary hypogonadism
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Species Reactivity:	Human, Mouse, Rat, Zebrafish
Antibody Description:	pdf
Recommended Dilutions::	WB: 1:1,000-1:5,000 ICC: 1:50-1:200 IHC: 1:50-1:200
Size:	100ul liquid