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CZRZ Catalog ID: CZ57
Availability: Frozen sperm
Genotype: closm0/+
Affected Gene: clo 
Genotyping: unspecified
GENOTYPE COMPOSITION
Genomic Feature Zygosity Parental Genotype Lab of Origin Construct
sm0 heterozygous Wenqing Lab
Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified
Note:
cloche mutant affects both the endothelial andhematopoietic lineages at a very early stage. The endocardium,the endothelial lining of the heart, is missing inmutant embryos. The myocardial cells form a tube that isdemarcated into chambers, beats rhythmically, butexhibits a reduced contractility. of the endothelialand blood lineages, possibly by affecting a common progenitorcell population.