China Zebrafish Resource Center (CZRC)

apoptotic process increased occurrence, eye decreased size, intestine decreased size

基准单价：

Commercial:¥2600(Adults)/Unit ¥1600(Embryos)/Unit ¥6000(Frozen sperm)/Unit
Non-commercial:¥1300(Adults)/Unit ¥800(Embryos)/Unit ¥3000(Frozen sperm)/Unit
Price Detail
The CZRC is a non-profit organization. The prices we charge for products and services are to offset some of the actual costs we incur.
Please acknowledge the CZRC in all publications resulting from the materials and/or services we are providing to you. Thank you!
Number:

CZRZ Catalog ID:	CZ44
Availability:	Frozen sperm
Genotype:	nup107^tsu068Gt/+
Affected Gene:	nup107 (si:dkey-27k7.3, zgc:152723)
Genotyping:	pdf

GENOTYPE COMPOSITION

Genomic Feature	Zygosity	Parental Genotype	Lab of Origin	Construct
tsu068Gt	heterozygous		Meng Lab	Gt(bcl2-EGFP)

Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified Background: AB Affectedgeneurl: unspecified Linetype: Mutant Previous Names: unspecified

Phenotype:

apoptotic process increased occurrence, eye decreased size, intestine decreased size

Note:

The Nup107–160 multiprotein subcomplex is essential forthe assembly of nuclear pore complexes. Homozygous nup107tsu068Gtmutant embryos exhibit tissue-specific defects after 3 days postfertilization(dpf), including loss of the pharyngeal skeletons,degeneration of the intestine, absence of the swim bladder, andsmaller eyes.In cells of the defective tissues, FGrepeatnucleoporins are disturbed and nuclear pore number isreduced, leading to impaired translocation of mRNAs from thenucleus to the cytoplasm.

CZRC Home | Guidelines for Ordering | Technical Service | FAQ | Contact Us

Web Support: Taizhou Xing-Ao Network Technology Co., Ltd.