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CZRZ Catalog ID: CZ272
Availability: Frozen sperm
Genotype: topbp1cas003/+
Affected Gene: topbp1
Genotyping: pdf
GENOTYPE COMPOSITION
Genomic Feature Zygosity Parental Genotype Lab of Origin Construct
cas003 heterozygous Weijun Pan Lab
Background: AB Affectedgeneurl: https://zfin.org/ZDB-GENE-060626-1 Linetype: Mutant Previous Names: unspecified Background: AB Affectedgeneurl: https://zfin.org/ZDB-GENE-060626-1 Linetype: Mutant Previous Names: unspecified
Note:
C to T nonsense mutation in topbp1 gene causing an earlier stop codon before the eighth BRCT (BRCA1 C-terminus) domain and a putative C-terminus nuclear localization signal (NLS) of TopBP1 protein